Can I combine nitrous oxide with other drugs?
Combining drugs always creates additional risks. It is therefore not recommended.
Combination with alcohol or other downers can increase the numbing effect of nitrous oxide and the risks.
Combination with psychedelics can provide an enhanced effect of the psychedelics. That can be fun, but it can also be too intense and cause a panic reaction. This chance of a panic reaction also applies to the combination with uppers.